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  • Drugs Discovery

    Overview
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    New Biologics Entity (NBE)
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  • Overview | Therapeutic Areas | Highlights

          
    Overview

    Glenmark is the leader in India in the Discovery of New molecules both NCEs (New Chemical Entity) and NBEs (New Biological Entity).

    Glenmark has a pipeline of 13 molecules – 8 NCEs & 5 NBEs in various stages of preclinical & clinical development.

    8 molecules are in clinical stage of development and 4 outlicensing deals have been struck with global pharma majors reaffirming Glenmark’s strength in discovery.

    Most molecules in clinical trials are either best-in-class or first-in-class with each molecule having potential peak sales opportunity ranging from USD 1 billion to USD 3 billion.

    Over 400 Scientists and extensive R&D facilities spread across the globe combine to form the hub of Glenmark’s R&D activity.

    Glenmark has three R&D centres dedicated for drug discovery. NCE research is conducted at the R&D centre in Navi Mumbai–India; NBE research is done at Neuchatel–Switzerland; and the Clinical R&D centre is located in Oxford, United Kingdom.


    Drug Discovery : Focus Therapeutic Areas
     
              
     
     
    Highlights : Molecules in Clinical Trials
     
    Crofelemer : Glenmark’s in–licensed molecule Crofelemer has the potential to be India’s first novel drug.
    Melogliptin : In the DPPIV class, Melogliptin has potential to be best-in-class in terms of safety and efficacy.
    GRC 15300 : Glenmark’s TRPV3 agonist GRC 15300 is the first molecule globally to enter clinical trials.
    GRC 10693 : The only selective CB–2 molecule currently reported in clinical development following the oral route of administration.
    Revamilast : A PDEIV inhibitor indicated for the treatment of Rheumatoid Arthritis, Multiple Sclerosis and other Inflammatory Pain.
    GBR 500 : Glenmark’s novel biological molecule for multiple sclerosis GBR 500 is the first molecule owned by an Indian company to enter clinical trials.
  • SCRIP Award